QRP Nutrition ASHWAGANDHA 600mg 100capsules
- Documented adaptogenic properties
- Protection of the cardiovascular system
- Emotional balance and stability
- Certified organic material
- Support of the organism’s immunity
- Better memory and concentration
- Increases resistance to stress
- Anti-inflammatory activity
- Increase of energy and vitality
- Proper for vegans
QRP Nutrition Ashwagandha Strong is a dietary supplement containing a high-quality extract obtained from a certified organic root of Withania somnifera - Ashwagandha, standardized for the content of 7% withanolides, 0.25% withaferin A and 1% alkaloids. The preparation contributes to increasing the organism’s immunity to stressors, the improvement of well-being and positively influences general health of the organism.
Withania somnifera, also known as Ashwagandha, is a plant known and used for thousands of years in the Indian system od natural medicine - Ayurveda, due to its exceptional properties. Ashwagandha has become an object of many scientific studies and currently it may be “proud” of abundant documentation, confirming its adaptogenic properties.
The root of Ashwagandha is the richest in the active compounds, as it contains i.a. alkaloids, withanolides A-Y, phytosterols, phenolic acids and minerals. The main compounds conditioning the activity of the plant are withaferin A and withanolide D, belonging to withanolides, however, increasingly more studies prove that bioactivity of this plant to a large extent is related to the content of other ingredients.
Withanolides have documented anticancer, antibacterial, cytostatic and calming properties. They also decrease blood pressure. Moreover, they demonstrate the ability to stabilize hormonal balance. The mechanism of activity of withanolides consists in i.a. sensitizing serotonin receptors 5-HT, intensifying the activity of serotonin. This is reflected in better mood, antidepressant and anti-stress effect and the increase of cognitive functions.
The best-known compound of the withanolide family is withaferin A. It has been demonstrated to be an inhibitor of the transcription factor Sp1, which is a regulating element in the expression of many genes, the so-called transcription activation domain. Sp1 affects the expression of the genes that participate in, for example, the process of cell apoptosis, growth, multiplication, aging, or carcinogenesis. Sp1 overexpression can be observed in many types of cancer and may signal poor outcome; therefore, the factor can be a potential target in anticancer therapy.
Adaptogens are a group of substances of plant origin, which have positive influence on the nervous system - they alleviate and counteract harmful effects of exposure to stressors by increasing adaptive abilities of the organism.
Ashwagandha increases adaptation of the organism to stress factors. The exposure of the organism to chronic stress entails many negative effects for the organism. Ashwagandha minimizes the consequences of long-lasting exposure to stress and supports regeneration of the organism after burden with long-lasting physical and mental effort. There is some evidence that Withania somnifera has anti-stress effect and reduces the level of cortisol, which is reflected in decreased fatigue, improved well-being, better vitality and s